The zebrafish has become an increasingly prevalent model: but in this series we are going to dive deeper, discussing their unique benefits.

As personalized medicine and the discovery of de novo variants that cause disease continue to grow, researchers are increasingly in need of alternative models

As personalized medicine and the discovery of de novo variants that cause disease continue to grow, researchers are increasingly in need of alternative models

As personalized medicine and the discovery of de novo variants that cause disease continue to grow, researchers are increasingly in need of alternative models

As personalized medicine and the discovery of de novo variants that cause disease continue to grow, researchers are increasingly in need of alternative models

The zebrafish has become an increasingly prevalent model: but in this series we are going to dive deeper, discussing their unique benefits.

Gut microbiota impacts nearly every aspect of health, but researching it can be tricky due to differences between humans and commonly

Inflammation in your intestine is detrimental to overall health, and can create many complications. So how is this phenomenon researched?

Zebrafish have an astonishing capacity for organ and appendage regrowth and could unlock the possibilities of human tissue regeneration.

The FDA announced animal testing no longer necessary for drug discovery. In this article we discuss the implications for USA’s drug pipeline.

The zebrafish has become an increasingly prevalent model: but in this series we are going to dive deeper, discussing their unique benefits.

The zebrafish has become an increasingly prevalent model: but in this series we are going to dive deeper, discussing their unique benefits.

Traditional modeling of patient variants in vivo has two limitations which can be overcome utilizing InVivo Biosystems’ patented WHAM-method.

In this article we discuss what President Biden’s New Executive Order means for America’s place in the biotech and biomanufacturing fields.

In this article we will discuss the collection of new gut-brain publications, and how their findings could influence the approach and treatment of neurodegenerative diseases

We are excited to announce that the USPTO has issued a patent titled, ‘Transgenic animal phenotyping platform and uses thereof’ to InVivo Biosystems.

Drs Pruyne & Amack leveraged InVivo Biosystems’ Custom Injection Mix to design and create a novel zebrafish line.

Summary: We recently published a piece on the importance of temperature in C.elegans which got the whole InVivio Biosystems team thinking about C. elegans’ development,

In this white paper we will discuss the advantages and limitations of zebrafish and ask: is a zebrafish model right for my research?

In this whitepaper we discuss the advantages and limitations of C. elegans, and ask the question: is a C. elegans model right for my research?

In this article we discuss the rise in gut dysbiosis, and new risk factors: microplastics, consumption of supplements, and chronic stress.

In this article, we will discuss the commonly used model organisms for microbiome research, and what insights they can provide.

This article will discuss recent findings, and how similar studies present an exciting and promising future for currently incurable diseases.

Summary Zebrafish models largely began as a way to research developmental biology, however, their potential to be a preclinical model of human disease quickly became

Beyond research into vaccines and traditional therapeutics, the medical community is exploring other ways of helping to prevent, and reduce, symptoms of COVID-19. One promising

Tauopathies are a type of neurodegenerative disease which get their name from the accumulation of Tau protein that occurs in all of them; these diseases

This article reviews the history of the zebrafish, and discusses the scenarios when other fish species are advantageous.

Mutations in the STXBP1 gene are implicated in childhood epilepsies and several neurodevelopmental disorders, however, nearly half of the STXBP1 variants recorded in the ClinVar

Using the models provided by InVivo Biosystems, the Starr & Luxton Labs were able to focus their efforts on understanding and evaluating the variants and

The Undiagnosed Diseases Network UND is a nationwide network that is working to understand and diagnose rare and undiagnosed human diseases. The UND coordinates between

The Undiagnosed Diseases Network brings together experts across the USA, combining clinical care and research to find diagnoses for undiagnosed patients. Zebrafish are extremely valuable

Using Humanization we can take advantage of the ancient biology between humans and other organisms to create stand-ins – patient avatars – for drug screening

A common saying in science is that, “good science and good animal welfare go hand in hand.” In this article we provide an overview of

Humanized animal models are becoming more widely used as new gene editing techniques become available and there is a push for a more personalized approach

Reactive oxygen species (ROS) are free radicals that have been found to extend lifespan at low levels, however, they are lethal at higher doses. So

New ‘humanized models’ have the potential to revolutionize the study of clinical diseases, creating models with higher validity than more traditional models. This in turn

Alzheimer’s disease is a progressive, debilitating disease that accounts for 60-80% of all dementia cases, however, it remains untreatable. In this blog, we provide an

According to the Epilepsy Foundation 1 in 26 people in the U.S.A will develop epilepsy at some point in their life, however, epilepsy is a

Model organisms are essential to experimental research, allowing researchers and scientists to address a variety of questions. While no model is perfect, some models are

A new finding has set the Alzheimer’s research world abuzz: a 73- year old woman with extremely high risk for AD, yet who doesn’t have

We have found whole gene humanization can create a platform for highly translatable results in a model organism. Currently there is a big need for

Did you know C. elegans are an ideal model for disease modeling? It may seem unlikely that such a tiny animal would work well for

With the advent of the molecular biology revolution and the human genome project in the 1990s there was a historic shift toward target-based drug

We created over 90 point mutations in the STXBP1 gene via CRISPR. A map of these point mutations can be seen above. Clinical variants

Our CSO, Dr. Chris Hopkins presented at DR. GPCR SUMMIT 2020 on why C. elegans is an ideal model to study the underlying principles of GPCRs.

Our CSO recently helped write a letter expressing the need for animal models in COVID-19 research

C. elegans and Zebrafish have been used to study the effects of ultraviolet radiation (UVR) for decades. August is Summer Sun Safety Month so in

Dr. Vollmer shares his experience working with us and how the Longevity Platform delivers the results he needs within his timeline and budget.

In an effort to create better models for epilepsy, we’ve been working on a grant-funded project to humanize important synaptic machinery by replacing endogenous coding

June is Alzheimer’s & Brain Awareness Month. We wanted to take a few moments to spotlight some of the awe-inspiring research on Alzheimer’s disease taking

Tune in weekly to our virtual series “Seventeen Minutes of Science” every Tuesday at 11am PST / 2pm ET where we go live on Facebook

Originally posted on the Enviral Tech website. Read it on their site here. Why you should start testing your facilities for COVID-19 now As COVID-19

We use the zebrafish (Danio rerio) as an in vivo model to measure the functional effects of patient-derived genetic variation.  In this way, human genetic variants identified

While advances in molecular imaging, high-throughput screening, genomics and techniques like CRISPR-Cas9 gene editing have dramatically enhanced our understanding of the human body and disease,

C. elegans as a model to evaluate the function of disease genes In 1998, the soil nematode Caenorhabditis elegans became the first multicellular organism of

Our CSO explores a theory he has about the amino acid arginine which seems to be showing frequent association with pathogenicity.

Neurotoxin exposure is implicated in the etiology of neurodegenerative diseases including Parkinson’s disease, Alzheimer’s disease and ALS (amyotrophic lateral sclerosis). Traditionally, vertebrate animals such as

NemaMetrix is the market leader for early preclinical in-vivo testing using small animal models to gain a better understanding of the efficacy, mode of action,

NemaMetrix is the market leader for early preclinical in-vivo testing using small animal models to gain a better understanding of the efficacy, mode of action,

How are extreme weather events, such as Hurricane Katrina, spreading heartworms and other parasitic nematodes and what are the implications of their spread?

How are extreme weather events, such as Hurricane Katrina, spreading heartworms and other parasitic nematodes and what are the implications of their spread?

Drug resistance in many pathogens — viruses, bacteria, protozoa, parasitic worms and more — presents a growing and potentially catastrophic challenge to human and animal

Our CSO revisits his Veritas Genomic Sequencing report for a closer look at how significant some of the discovered variants are

NemaMetrix is the market leader for early preclinical in-vivo testing using small animal models to gain a better understanding of the efficacy, mode of action,

The shift towards preventive medicine has given anti-aging startups a favorable environment in pursuing longevity and aging issues. The nematode C. elegans has emerged to

NemaMetrix is the market leader for early preclinical in-vivo testing using small animal models to gain a better understanding of the efficacy, mode of action,

Animal testing in the research-based pharmaceutical industry has been reduced in recent years both for ethical and cost reasons. However, it is still a staple

When you receive your genomic report, you have a movement of trepidation.What will it say? Will it have something that says you should do countermeasures

In 2017, a now-redacted paper published in Nature Methods claimed that CRISPR created hundreds of unintended mutations in mouse models, and that algorithms designed to