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InVivo Biosystems Blog

Category: Drug Discovery

humanized models for drug discovery and development
Humanized Models: Shaping the Future of Drug Discovery and Development
By:
Ally Wimberly ,
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Huntington’s Disease: Revolutionizing Drug Discovery with Fast In Vivo Models
By:
Ally Wimberly ,
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Parkinson’s Takes Decades to Develop–Zebrafish Provides Answers Within Days.
By:
Laura Taggart-Murphy ,
Ally Wimberly ,
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Unraveling Epilepsy: Modeling Dravet Syndrome in Zebrafish
By:
Joseph Bruckner ,
Stacy Levichev ,
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Alternative Animal Models Unlock Hope in STXBP1 Epilepsy Research
By:
Ally Wimberly ,
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Rapid Results: The RapidGen™ CRISPR Approach
By:
Ally Wimberly ,
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Speeding up the diagnostic journey for Rare Disease patients: An in vivo discovery platform that helps classify variants of uncertain significance
By:
Chris Hopkins ,
Alexandra Narin ,
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How to Attain IND Approval Faster
By:
Ally Wimberly ,
Alexandra Narin ,
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Fast, Cost Effective Compound Efficacy Testing using Zebrafish
By:
Alexandra Narin ,
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Leaky gut assays feature image
Leaky Gut Assays in Animal Models
By:
Alexandra Narin ,
Chris Hopkins ,
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FDA Modernization Act 3.0: Alternative Animal Models are Transforming Drug Development
By:
Alexandra Narin ,
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WHAM with CRISPR - re-imaging how rare disease therapeutics are developed
Whole-gene Humanized Animal Models (WHAM) with CRISPR – Re-imagining how Rare Disease therapeutics are developed
By:
Chris Hopkins ,
Alexandra Narin ,
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customer story: zebrafish CRO feature image
Using Zebrafish Custom Injection Mixes to Accelerate the Grant Application Process
By:
Alexandra Narin ,
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WHAM - humanized animal models for drug discovery
WHAMyness – How Gene-Humanized Animals Can Dramatically Improve Drug Discovery
By:
Chris Hopkins ,
Alexandra Narin ,
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America is finally investing in Biotechnology & Biomanufacturing in a Big Way
By:
Alexandra Narin ,
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The Path to Affordable Therapeutics in Rare Disease – Tackling Congenital Disorder of Glycosylation in the PMM2 gene [Customer Story].
By:
Hannah Huston ,
Alexandra Narin ,
Chris Hopkins ,
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[Patent Announcement] InVivo Biosystems has officially been issued a patent on WHAM-humanization in the nematode, C. elegans
By:
Alexandra Narin ,
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Looking at Gene Paralogs across both zebrafish and C. elegans Model Organisms [Customer Story]
By:
Alexandra Narin ,
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Part Two: Is Drug Repurposing the New Model for Drug Discovery?
By:
Astha Nimavat ,
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Part One: An Overview of Drug Repurposing
By:
Astha Nimavat ,
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Chemicals Models of Parkinson’s Disease in Larval Zebrafish
By:
Laura Taggart-Murphy ,
Alexandra Narin ,
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Poking its way into Western Medicine: How Acupuncture Could Help Ease Chronic Pain
By:
Alexandra Narin ,
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A Natural Fit – Using Zebrafish to Evaluate Natural Compounds for Anti-Inflammatory Properties
By:
Laura Taggart-Murphy ,
Alexandra Narin ,
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Quick Guide to Natural Products: What They are and How They Impact You
By:
Alexandra Narin ,
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zfish as drug discovery tool feature image
Lost and Found: Zebrafish as a Drug Discovery Tool
By:
Alexandra Narin ,
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Neuroscience Models: Transgenic Mice, Zebrafish, C. Elegans – And Jellyfish?
By:
Alexandra Narin ,
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From ED to AD: a drug repurposing success? How a performance-enhancing drug is giving insight into dementia
By:
Alexandra Narin ,
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The In (vitro, vivo, silico)s and Outs of Research
By:
Alexandra Narin ,
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The Discrepancy Between Sexes: Clinical Models & Clinical Trials
By:
Alexandra Narin ,
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A Closer Look at Nutraceutical Regulations: How Does the USA Compare?
By:
Alexandra Narin ,
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Recent Nutraceutical Research
By:
Alexandra Narin ,
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Testing the Neuroprotective Effect of a Lead Compound Using C. elegans for Fast and Cost-Effective Answers [Customer Story]
By:
Hannah Huston ,
Alexandra Narin ,
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FDA versus FTC Approval – What is the Difference?
By:
Alexandra Narin ,
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HIV, COVID-19, Alzheimer’s: The Impact of The FDA’s Expedited Programs and What’s Next
By:
Alexandra Narin ,
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Fast-tracking Medicines to Patients in Need: Navigating the FDA’s Expedited Tracks to Accelerate Your Drug Discovery and Development.
By:
Alexandra Narin ,
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New Alzheimer’s Drug: Helpful or Just Expedient?
By:
Alexandra Narin ,
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Rising Healthcare Costs? Non-Mammalian Models To The Rescue
By:
Alexandra Narin ,
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Let’s Fail Faster: Why Scientific Failures Should be Accepted as Progress
By:
Alexandra Narin ,
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The DrugAge Database: Showcasing C. Elegans In Longevity Research
By:
Alexandra Narin ,
Trisha Brock ,
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Drug Repurposing for Neurological Disorders
By:
Alexandra Narin ,
Neurological disorders are extremely widespread, affecting over 1 billion people worldwide, and have debilitating effects, impacting the brain, spinal cord, cranial nerves, and peripheral nerves.
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Whole Gene Humanization for Personalized Medicine Applications
By:
Chris Hopkins ,
We have found whole gene humanization can create a platform for highly translatable results in a model organism. Currently there is a big need for
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How to Design a Good Phenotype Based Drug Discovery Program, and Why It Matters.
By:
Kathryn McCormick ,
With the advent of the molecular biology revolution and the human genome project in the 1990s there was a historic shift toward target-based drug development.
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Understanding GPCRs Using Humanized C. elegans
By:
InVivo Biosystems ,
Our CSO, Dr. Chris Hopkins presented at DR. GPCR SUMMIT 2020 on why C. elegans is an ideal model to study the underlying principles of
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Seventeen Minutes of Science: Viral Gene Therapies and Their Potential Use Against COVID-19
By:
InVivo Biosystems ,
Tune in weekly to our virtual series “Seventeen Minutes of Science” every Tuesday at 11am PST / 2pm ET where we go live on Facebook
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Seventeen Minutes of Science: Spreading out from Kendall (Episode 6)
By:
Hannah Huston ,
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Zebrafish and C. elegans in ALS: tightening the bench-to-clinic gap
By:
InVivo Biosystems ,
While advances in molecular imaging, high-throughput screening, genomics and techniques like CRISPR-Cas9 gene editing have dramatically enhanced our understanding of the human body and disease,
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wMicroTracker Applications: Drug Screening
By:
Yoanne Clovis, Ph.D. ,
The wMicroTracker is a great product to add to your drug screening toolkit. Check out the application sheet below to see how easy it is
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