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Author: Alexandra Narin

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Disease Modeling

Leaky Gut Assays in Animal Models

Summary:  Over the past decade there has been an explosion in people experiencing gastrointestinal issues, and, consequently, there has been increased interest in research looking

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CRISPR

Zebrafish 101: A White Paper

Summary From pet to model organism, zebrafish have made impressive strides since the 1960s, when George Stresinger pitched its use in research. In this white

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CRISPR

The State of Knock-ins in Zebrafish

Summary Knock-ins enable testing of a gene’s function through introducing precise mutations or attaching tags. Creating knock-ins in zebrafish presents it own unique challenges due

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Disease Modeling

An Updated Comparison of Common Model Organisms Part 2: Organisms for Modeling Epilepsy

According to the Epilepsy Foundation 1 in 26 people in the U.S.A will develop epilepsy at some point in their life, however, epilepsy is a very diverse condition which makes researching it especially challenging. In this blog, we will discuss the model organisms commonly used in epilepsy research, and how their characteristics act as advantages and limitations when modeling epilepsy.

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Disease Modeling

An Updated Comparison of Common Model Organisms

Model organisms are essential to experimental research, allowing researchers and scientists to address a variety of questions. While no model is perfect, some models are more suitable for investigating specific questions than others. In this blog, we provide an overview of many commonly used model organisms, and compare their advantages and limitations.

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Drug Discovery

Drug Repurposing for Neurological Disorders

Neurological disorders are extremely widespread, affecting over 1 billion people worldwide, and have debilitating effects, impacting the brain, spinal cord, cranial nerves, and peripheral nerves. Despite this, many neurological disorders lack effective treatment. One strategy that offers an attractive way to find better therapies is drug repurposing. Also known as drug reprofiling or drug repositioning, drug repurposing identifies new purposes for pre-existing compounds, and offers reduced time frames, decreased costs, and improved success rates. While drug repurposing for neurological disorders has gained attention in the past decade, it is still an underused approach. In this article we will discuss drug repurposing, its benefits, its place in neurological drug research, and its recent success.

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