History of CRISPR: Cas9 and Cas12
We discuss the history of two of the most widely studied Cas proteins and how they are shaping the future of research and medicine.
CRISPR
Differences Between HDR vs NHEJ
Summary The CRISPR-Cas9 system has become integral in the toolbelts of genomic scientists, researchers, students, etc. Never has it been so easy to wield a pair of molecular scissors in your (pipetting) hand, however, there are a few intracellular processes to consider before cutting up your genome of interest. In this article, we will give …
How do Knockins Work?
In this article we compare and contrast several knock-in methodologies. So how do knock-ins work? Continue reading to find out!
The ABCs of Genetic Research
Here at InVivo Biosystems we spend a lot of time thinking, and talking, about genome editing. We thought it would be fun to compile a list of our frequently used terms – so here they are, our ABCs of genetic research.
Zebrafish 101: A White Paper
In this white paper we will discuss the advantages and limitations of zebrafish and ask: is a zebrafish model right for my research?
C. elegans 101: A White Paper
In this whitepaper we discuss the advantages and limitations of C. elegans, and ask the question: is a C. elegans model right for my research?
Nutraceuticals & New approaches to DMD treatment
This article will discuss recent findings, and how similar studies present an exciting and promising future for currently incurable diseases.
Neuroscience Models: Transgenic Mice, Zebrafish, C. elegans – and Jellyfish?
In this article we discuss Weissbourd’s recent publication as well as GCaMP more broadly, showing how advancing technology has enabled researchers to ask questions that span disciplines and model organism species.
What is Zebrafish Knock-in Tagging?
With knock-in tagging, you can tag your favorite gene at the native locus in your zebrafish line via CRISPR/Cas9 gene editing technology.
The State of Knock-ins in Zebrafish
The recent advancements of CRISPR and next-generation technology has enabled researchers to create more precise zebrafish models of human disease. This being said, knock-in (KI) techniques in zebrafish still aren’t fully optimized. In this article we discuss the current state of CRISPR-Cas9-mediated targeted knock-ins in zebrafish, and what the future holds.