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Compound Effects Testing Platform For Microbiome Study

Gut Microbiome Study Service: Advancing Research Using Zebrafish and C. elegans Models

The microbiome is a relatively new area of research. They were formerly dominated by mammalian rodent studies, but more and more researchers are finding that alternative models such as zebrafish and C. elegans can offer the ability to perform large-scale observational studies, with low maintenance cost, and yet not sacrifice translatability. These organisms can help answer both fundamental questions about the role of microbes, and the underlying mechanisms involved in the pathway, contributing to fascinating discoveries in the study of gene expression.

  • Monitor survival and movement to compare lifespan and healthspan.
  • Conduct transcriptomics study to determine the role of the underlying genetics in creating these health benefits (aka mechanism of action).
  • Kaplan-Meier estimate of survival function

  • Descriptive statistics and tests for differences between groups

LIFESPAN SAMPLE DATA

Advantages

Our unique workflows and capabilities can get you the data you need in as little as 3 months, showcasing the turnaround time efficiency. We can:

As a result:

Service Offerings

Data Only

Data Interpretation

Data Customization

Timeline

2-3 months

2-3 months

2-3 months

Resources

Study Report

Vitality & Antioxidant Study Report – an example of a client project report. 

What is the microbiome? How does it help or hinder health? And, what
does recent research indicate?

Gut Microbiome Study Service FAQs

1. What is a Gut Microbiome Study Service?

Answer: Gut Microbiome Study Service is a cutting-edge research platform that leverages high-throughput sequencing technologies and microbiome sequencing services to explore the complex world of microbial communities within the human gut. By studying microbial diversity and microbial genomics, these services offer valuable insights into how the gut microbiota impacts human health, disease, and drug development. Utilizing models like zebrafish and C. elegans, researchers can conduct functional profiling and analysis of gene expression to understand the microbiome’s role in health and disease.

2. How can Gut Microbiome Study Service benefit research in drug development and clinical trials?

Answer: Gut Microbiome Study Service plays a vital role in drug development and clinical trials by providing comprehensive microbiome profiling and microbiome gene expression analysis. This allows for the identification of beneficial bacteria, the exploration of metabolic pathways, and the understanding of microbial effects on human gut microbiota. Such detailed insights facilitate the development of targeted probiotics, novel therapeutics, and personalized medicine approaches, significantly impacting patient health and treatment outcomes.

3. What technologies are used for microbiome analysis in Gut Microbiome Study Services?

Answer: Gut Microbiome Study Services utilize advanced sequencing technologies such as next-generation sequencing (NGS), amplicon sequencing, and shotgun metagenome sequencing. These technologies offer species-level resolution and taxonomic resolution, enabling deep sequencing of the rRNA genes and providing a comprehensive view of the microbial composition. Through high-throughput sequencing, researchers can achieve accurate microbiome quantification and functional profiling, essential for understanding microbial ecology and its impact on the human body.

4. What makes zebrafish and C. elegans models ideal for Gut Microbiome Study Services?

Answer: Zebrafish and C. elegans are ideal models for Gut Microbiome Study Service due to their simplicity, cost-effectiveness, and ease of observing microbiome shifts and microbial flora interactions. These models allow for high-throughput screening and microbiome sample analysis in a controlled environment, making them invaluable for studying microbial genomics, microbial ecology, and the human gut microbiome. Their use accelerates the turnaround time for microbiome insights, facilitating fascinating discoveries in the field of microbiome analysis.

5. How does Gut Microbiome Study Service contribute to understanding the human gut microbiota and human health?

Answer: Gut Microbiome Study Service contributes significantly to our understanding of the human gut microbiota by providing microbiome profiling and microbiome gene expression analysis. This detailed analysis helps uncover the complex interactions between microbial species and their impact on human health, including nutrient absorption, immune function, and disease resistance. By exploring the microbial diversity within the human gut microbiome, these services offer valuable insights into microbiome shifts, gut dysbiosis, and their correlations with various health conditions, paving the way for microbiome-based therapeutic strategies.

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