The Nutraceutical market has exploded over recent years, it was valued at $278.8 billion USD in 2020, and is expected to continue growing at a rate of 7.8% – reaching $441.7 billion USD by 2026 (ReporterLinker, 2021). With that forecast it is no wonder that there has been an increased interest in researching nutraceutical ingredients and their effects. Coupled with the growing market potential, is the regulatory concern which is making more comprehensive testing necessary.
Image 1. Comparison of nutraceuticals and pharmaceuticals. Nutraceuticals can be consumed via normal food, as ingredients with naturally high contents or as substances being enriched in a food matrix. In contrast, pharmaceuticals are products that are developed for a specific medical application (Sauer & Plauth, 2017).
We’ve rounded up some of the recent publications that we’ve been enjoying – click their links below to see what’s new in this space!
- Cary, M., Podshivalova, K., & Kenyon, C. (2020). Application of Transcriptional Gene Modules to Analysis of Caenorhabditis elegans‘ Gene Expression Data. G3 (Bethesda, Md.), 10(10), 3623-3638. https://doi.org/10.1534/g3.120.401270
- Zhang, F., Berg, M., Dierking, K., Félix, M. A., Shapira, M., Samuel, B. S., & Schulenburg, H. (2017). Caenorhabditis elegans as a Model for Microbiome Research. Frontiers in microbiology, 8, 485. https://doi.org/10.3389/fmicb.2017.00485
- Arey, R. N., & Murphy, C. T. (2017). Conserved regulators of cognitive aging: From worms to humans. Behavioural brain research, 322(Pt B), 299-310. https://doi.org/10.1016/j.bbr.2016.06.035
- Melzer D, Pilling LC, Ferrucci L. (2020). The genetics of human ageing. Nature reviews. Genetics.(2):88-101. DOI: 10.1038/s41576-019-0183-6. PMID: 31690828.
- Christian, C. J., & Benian, G. M. (2020). Animal models of sarcopenia. Aging cell, 19(10), e13223. https://doi.org/10.1111/acel.1322
- Wani, K. A., Goswamy, D., & Irazoqui, J. E. (2020). Nervous system control of intestinal host defense in C. elegans. Current opinion in neurobiology, 62, 1-9. https://doi.org/10.1016/j.conb.2019.11.007
- Licitra, R., Marchese, M., Brogi, L., Fronte, B., Pitto, L., & Santorelli, F. M. (2021). Nutraceutical Screening in a Zebrafish Model of Muscular Dystrophy: Gingerol as a Possible Food Aid. Nutrients, 13(3), 998. https://doi.org/10.3390/nu13030998
- Stuhr, N.L., Curran, S.P. Bacterial diets differentially alter lifespan and healthspan trajectories in C. elegans. Commun Biol 3, 653 (2020). https://doi.org/10.1038/s42003-020-01379-1
- Catalani, E., Fanelli, G., Silvestri, F., Cherubini, A., Del Quondam, S., Bongiorni, S., Taddei, A. R., et al. (2021). Nutraceutical Strategy to Counteract Eye Neurodegeneration and Oxidative Stress in Drosophila melanogaster Fed with High-Sugar Diet. Antioxidants, 10(8), 1197. MDPI AG. Retrieved from http://dx.doi.org/10.3390/antiox10081197
- Dai, W., Wang, H., Fang, J., Zhu, Y., Zhou, J., Wang, X., Zhou, Y., & Zhou, M. (2018). Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathway. Brain research bulletin, 140, 65-71. https://doi.org/10.1016/j.brainresbull.2018.03.020