Zebrafish Knockout Packages

Zebrafish Knockout Service

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Gene knockouts are a commonly used tool for biologists to understand gene function. Examination of phenotypes when the gene is deleted can reveal insights into what role that gene plays in the organism.

Using CRISPR/Cas9, we can delete integral domains or the entire the coding sequence of a gene in zebrafish, depending on gene size. We have generated lesions ranging from small indels to full gene deletions.

If deletion of your gene is lethal, consider making a floxed allele.

Service Options (price reflects academic pricing)

Service PackagePriceEst. Delivery Time
Full Build $26,9559 - 12 months
Verified Clutch $9,3104 - 6 months
Custom Injection Mix (without verification of sgRNA cutting)
$9954-6 weeks
Custom Injection Mix (with verification of sgRNA cutting) $3,2594 - 8 weeks

Knockout Publications

  • Eyes shut homolog is required for maintaining the ciliary pocket and survival of photoreceptors in zebrafish

    Yu, M; Liu, Y; Li, J; Natale, BN; Cao, S; Wang, D; Amack, JD; Hu, H. Biol Open. 2016 Nov 15;5(11):1662-1673.

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