We offer 3 strains and genes that are associated with the Alzheimer’s disease. The genetic identity of each strain has been validated with PCR and sequencing.
- PSEN1 Knock-out (Cat. No. ALZ-001)
- Humanized Aβ (Cat. No. ALZ-002)
- Humanized MAPT (Cat. No. ALZ-003)
Choose from 3 different packaging formats for each strain: Vial (frozen); Petri plate (room temperature); 96-well plate (room temperature)
Fig 1. Day-2 ALZ PSEN1 Knock-out live worm on NGM plate. This worm was dyed with both RediStain™ WormDyes Lyso (magenta) and Neuro Green (cyan) to stain sensory neurons and apoptotic corpses in the gonad respectively. The sel-12(ty11) mutation produces defects in vulva and neuronal development leading to a dysfunctional uterine-vulval connection and ultimately the inability to lay eggs. The worm is positioned head-down on the left and head-up on the right.