HomeInVivo Biosystems BlogNewsletterBi-Weekly Newsletter: 4.03.2020

Bi-Weekly Newsletter: 4.03.2020

NemaMetrix Expands Business to Capitalize on In-vivo Solutions to Help Speed Testing for Critical Disease Therapeutics

Company Changes Operating Name to InVivo Biosystems

Eugene, Ore. – March 31, 2020 – NemaMetrix is changing its operating name to InVivo Biosystems as the company expands its research platforms to accelerate deep in-vivo insights that help researchers develop and deliver therapeutic solutions for critical diseases. The company’s solutions now provide essential services to pharmaceutical, nutraceuticals, and biotechnology companies around the world to speed research and drug development efforts, enabling earlier insights by closing the gap between cells and mice. The company’s new capabilities help address some of today’s healthcare gaps, including worldwide efforts to combat COVID-19.

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Featured Findings:

  • To truly validate your sgRNAs, go In Vivo 
    • One way to enable researchers to initiate a project with confidence in the reagents they've selected is to rigorously test their sgRNA site. In fact we have found that validating sgRNA cutting efficiency is a critical step to mitigate failure rates in everything from null generation to homology driven repair and precise knock in... Read more
  • 6 things that can go wrong while making your Zebrafish CRISPR Knock-In
    • With so many tools at our disposal, and an increasing number of published examples of knock-ins making it seem relatively straightforward, why is it still so difficult? Why do so many skilled researchers toil at the bench for months, even years on these projects, often with little to show for it? One of our zebrafish experts discusses the biggest pitfalls, pain points and precautions our team has encountered at the bench and in the zebrafish community before you embark on your own knock-in odyssey. Read more
  • Neural excitation linked to shorter lifespan 
    • Increased neural activity was linked to a shorter lifespan, according to a study funded in part by NIA and published in Nature. The study was conducted using both C. elegans models and mouse models, in addition to human brain tissue, highlighting the importance of using multiple models. The research suggests that suppressing electrical activity in the brain could lead to a longer life. Read more
  • Genetic Control of Collective Behavior in Zebrafish
    • We as a species evolved to live and move in groups with complex social behaviors, and disruptions to these social interactions (like an emergent pandemic) can impact us in profound and difficult ways, particularly with respect to our mental health. In the coming weeks, perhaps we can take some time to reflect on the ways mental health disorders impact some people every day, even when there isn't a virus shutting down coffee shops and social gatherings. Social processing deficits in psychiatric disorders like autism and schizophrenia are poorly understood, but researchers are taking steps to understand the underlying genetics and behaviors of these disorders. Read on to learn more about how mutations in genes linked to human psychiatric disorders can alter zebrafish group behaviors. Read more

P.S.

Are you wondering if there is a way for you and/or your lab to help in the fight against COVID-19? There is! Join the group of 7K+ molecular biologists, biochemists, microbiologists, etc. who are seeking to offer their volunteer services for COVID-19 testing. The goal of the group is to accelerate testing pace and capability locally, statewide and nationally. Join the list

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