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Zebrafish and C. elegans in ALS: tightening the bench-to-clinic gap

While advances in molecular imaging, high-throughput screening, genomics and techniques like CRISPR-Cas9 gene editing have dramatically enhanced our understanding of the human body and disease, the pace of advancing new treatments for those diseases has lagged behind significantly. One way to shorten the time between laboratory discoveries and available new drugs is to use animal …

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Reviewers’ Choice Abstract Award at ASHG Goes to Ben Jusilla for Demonstrating how Zebrafish Can be Used for Disease Modeling

Ben Jusilla, one of our in-house zebrafish experts, presented his poster “Zebrafish modeling for the clinic: Rapid in vivo functional testing of patient variants for clinical applications” at ASHG and won the Reviewers’ Choice Award in the category of Precision Medicine, Pharmacogenomics, and Genetic Therapies. His poster discusses how we use zebrafish as an in-vivo model to measure …

Reviewers’ Choice Abstract Award at ASHG Goes to Ben Jusilla for Demonstrating how Zebrafish Can be Used for Disease Modeling Read More »

Using Zebrafish for Rapid Genetic Analysis

The introduction of engineered site-specific DNA endonucleases has brought precise genome editing in many model organisms into the realm of possibility. Thanks to precise and efficient genome editing in zebrafish using the CRISPR/Cas9 system, scientists at NemaMetrix are using zebrafish for rapid genetic analysis. Utilizing morphants and crispants you can…

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