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InVivo Biosystems Blog

Deciphering Breast Cancer with C. elegans – A Case Study
In recent years, the nematode C. elegans has emerged as a model for systematic dissection of the molecular basis of tumorigenesis. Many cancer genes and
Modeling Rare Diseases in Caenorhabditis elegans
There are approximately 7,000 rare diseases in humans, ~80% of which are monogenic. A rare disease is defined as affecting less than one in 1,500
Aging studies use C. elegans to test bacterial genes
Interesting data using C. elegans for studying the impact your gut microbiome may have on your lifespan and healthspan from the Wang Lab at Baylor
New phenotype discovered for NPC disease using C. elegans
We discovered that in the absence of cholesterol, NPC mutants display a lower pharyngeal pumping frequency and a longer duration between pumps than control N2 animals.
The cerebellum of a brain affected by Niemann-Pick Type C; blue staining shows the dense pockets of lipid accumulations throughout the brain
Searching for a cure for Niemann-Pick Type C using C. elegans
Niemann-Pick Type C is a rare and fatal disorder affecting children. We explore the efficacy of new potential therapeutics with the ScreenChip System.
Duration of pharyngeal contraction
Health markers are impaired in aging C. elegans
C. elegans’ feeding behavior strongly influences the worm’s aging and longevity. We tested adult worms to quantify how aging affects their feeding behavior. In
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