HomeInVivo Biosystems BlogModeling Rare Diseases in Caenorhabditis elegans

Modeling Rare Diseases in Caenorhabditis elegans

There are approximately 7,000 rare diseases in humans, ~80% of which are monogenic. A rare disease is defined as affecting less than one in 1,500 people. Combined, these rare diseases affect nearly 1 in 10 Americans (25 to 30 million people), and treatments only exist for around 5% of these diseases. Thanks to the advent of whole genome sequencing, the gene(s) responsible for many rare diseases are known, opening the door for more comprehensive studies.

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