Zebrafish Mutagenesis Packages

Zebrafish Point Mutation Service

showcase_point-mutation

The Point Mutation service using zebrafish introduces a small number of nucleotide changes at a target site using CRISPR/Cas9. With this service you can:

  • study a disease-causing mutation
  • humanize a critical amino acid
  • explore the binding site of an enzyme
  • introduce phosphomimetics
  • mutate isoform start sites or make any specific mutation of interest.

Precise Point Mutation of Stxbp1a in Zebrafish

Illustration of a successful precise point mutation of Stxbp1a in Zebrafish. Stxbp1a is a highly conserved zebrafish ortholog of human STXBP1 (87% identity). Using CRISPR/Cas9 technology, we were able to precisely generate a benign patient mutation at the conserved amino acid residue (CCC>CTG, p.P94L).

ZBF-STXBP1_copy

Service Offerings (price reflects academic pricing)

Service PackagePriceEst. Delivery Time
Full Build $26,9559 - 12 months
Verified Clutch* $9,3104 - 6 months
Custom Injection Mix (without verification of sgRNA cutting) $995 4-6 weeks
Custom Injection Mix (with verification of sgRNA cutting) $3,259 4 - 8 weeks
*Verified Clutch service is only available to customers in the United States.
READY TO GET STARTED?

Ready to connect with us to learn more about working with our company or our technology?

Scroll to Top