C. elegans MosSCI Service
The MosSCI service enables you to integrate your desired sequence as a single copy insertion at a designated locus in the C. elegans genome. This is advantageous as it allows you to leave the native gene unmodified. With the MosSCI service you can:
- Integrate a humanized gene into the C. elegans genome
- Integrate your gene of interest into the genome with a fluorescent tag
- Integrate your gene of interest into the genome with an immunotag
- Examine your gene of interest’s expression under the control of a different promoter
MosSCI Service Options (price reflects academic pricing)
|Service Package||Price||Est. Delivery Time|
|Full Build||$4,215 - $5,465||6 - 8 Weeks|
|Candidate Lines||$2,549 - $3,799||4 - 6 Weeks|
|Custom Injection Mix||$1,275 - $1,790||1 - 2 Weeks|
Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture
Jamie B. Harrisa, Jessica H.Hartman, Anthony L. Luz, Joanna Y. Wilson, Audrey Dinyaria, Joel N.Meyer.Toxicology Volume 440, July 2020, 152473.
Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?
Carvalho, RN; Arukwe, A; Ait-Aissa, S; Bado-Nilles, A; Balzamo, S; Baun, A; Belkin, S; Blaha, L; Brion, F; Conti, D; Creusot, N; Essig, Y; Ferrero, VE; Flander-Putrle, V; Fürhacker, M; Grillari-Voglauer, R; Hogstrand, C; Jonáš, A; Kharlyngdoh, JB; Loos, R; Lundebye, AK; Modig, C; Olsson, PE; Pillai, S; Polak, N; Potalivo, M; Sanchez, W; Schifferli, A; Schirmer, K; Sforzini, S; Stürzenbaum, SR; Søfteland, L; Turk, V; Viarengo, A; Werner, I; Yagur-Kroll, S; Zounková, R; Lettieri, T. Toxicol Sci. 2014 Sep;141(1):218-33.