C. elegans Behavior & Phenotyping Capabilities

C. elegans Behavior & Phenotyping

Embryo Viability

Reveal developmental effects of mutations and compound treatment by quantifying embryo viability.

Measuring embryo lethality. NMX410 and NMX421 have a much higher percent embryo lethality than N2 wild-type and several other samples.

  • APPLICATIONS

    Mutations and compounds can affect animal viability. Embryo viability can reveal developmental effects of mutations and compound treatment.

  • ASSAY DESCRIPTION

    Adult C. elegans are allowed to lay eggs on a plate for 2 hours. A set number of embryos are moved to a new plate. After 24 hours of incubation at 20℃, the number of unhatched embryos is counted.

  • DATA COLLECTED

    The percentage of embryo lethality is calculated from the unhatched embryos divided by the total number of embryos plated. Three replicates are tested.

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