HomeC. elegans

C. elegans

Worming into Relevance – How C. elegans Can Help us Understand Human Health

Animal testing in the research-based pharmaceutical industry has been reduced in recent years both for ethical and cost reasons. However, it is still a staple when it comes to discovering new compounds directed at improving human health. Recently, we have come across more and more researchers who are looking for the most efficient way to move …

Worming into Relevance – How C. elegans Can Help us Understand Human Health Read More »

Zebrafish and C. elegans in ALS: tightening the bench-to-clinic gap

While advances in molecular imaging, high-throughput screening, genomics and techniques like CRISPR-Cas9 gene editing have dramatically enhanced our understanding of the human body and disease, the pace of advancing new treatments for those diseases has lagged behind significantly. One way to shorten the time between laboratory discoveries and available new drugs is to use animal …

Zebrafish and C. elegans in ALS: tightening the bench-to-clinic gap Read More »

CRISPR technologies enable humanized animal models to aid disease research

C. elegans as a model to evaluate the function of disease genes In 1998, the soil nematode Caenorhabditis elegans became the first multicellular organism of which the genome has been sequenced completely [1]. One surprising result of this approach was that ~65% of the human disease genes have a counterpart in the worm [2]. In …

CRISPR technologies enable humanized animal models to aid disease research Read More »

Scroll to Top