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Alzheimer’s and Epilepsy Panels

New product releases from NemaMetrix

As a young and growing company, we are trying to design and introduce new products that can better serve your research needs. We’d like to share what we are working on. Sign up for notification and win a cool t-shirt.

C. elegans in cancer research

In recent years, the nematode C. elegans has emerged as a model for systematic dissection of the molecular basis of tumorigenesis. Many cancer genes and pathways are highly conserved and often easier to parse in C. elegans as the gene families involved contain fewer members, reducing genetic redundancy.

Deciphering Breast Cancer with C. elegans – A Case Study

In recent years, the nematode C. elegans has emerged as a model for systematic dissection of the molecular basis of tumorigenesis. Many cancer genes and pathways are highly conserved and often easier to parse in C. elegans as the gene families involved contain fewer members, reducing genetic redundancy. This case study illustrates how C. elegans were used to decipher breast cancer. 

Caenorhabditis elegans: An Emerging Model Organism

Great article that highlights some of the strengths of C. elegansfor investigating higher level processes beyond what can be easily studied using cell culture. In this case alternative pre-mRNA splicing. Also helped expose me to the a new descriptor for C. elegans worms – intron-rich.

Modeling Rare Diseases in Caenorhabditis elegans

There are approximately 7,000 rare diseases in humans, ~80% of which are monogenic. A rare disease is defined as affecting less than one in 1,500 people. Combined, these rare diseases affect nearly 1 in 10 Americans (25 to 30 million people), and treatments only exist for around 5% of these diseases. Thanks to the advent of whole genome sequencing, the gene(s) responsible for many rare diseases are known, opening the door for more comprehensive studies.

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