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NemaMetrix Introduces Fluorescent Staining Kits for Improved Phenotyping in model organism C. elegans

NemaMetrix, a company developing nematode-based drug development and screening technologies, announced the launch of its first series of RediStain™ fluorescent kits for improved visualization of C. elegans’ structure and function in phenotyping studies. These kits expand the toolkit of C. elegans research to include the ability to perform structural and functional assays that are standard in cell biology.

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New phenotype discovered for NPC disease using C. elegans

We discovered that in the absence of cholesterol, NPC mutants display a lower pharyngeal pumping frequency and a longer duration between pumps than control N2 animals. This is the progress we made in our collaborative research project with Perlara and investigation into the lysosomal disorder, Niemann-Pick Type C (NPC).

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Worms, Flies or Fish? A Comparison of Common Model Organisms – Part 1: Models for Biomedical Research

Non-mammalian model organisms are typically used in early research to deliver fast answers to a discovery problem. The most popular model organisms in biological and biomedical research are the fruit fly Drosophila melanogaster, the zebrafish and the nematode C. elegans. We provide a comparison of the advantages and limitations of many commonly used model organisms.

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Are worms the future of drug development?

NemaMetrix’s ScreenChip collects live-animal, high-throughput C. elegans electropharyngeograms (EPGs), which are an indication of overall organism health for drug development. Read the blog post on BioCoder published by O’Reilly Bio.

ScreenChip Platform Recognized by the White House

The NemaMetrix ScreenChip platform technology was recognized by the White House as one of the breakthrough life science research technologies. CEO Matt Beaudet spoke with Dr. Robbie Barbero of the US White House Office of Science and Technology Policy, who created a post on the White House website about the promise of new research technologies.

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