HomeArchives for Kathryn McCormick

Kathryn McCormick

FAVOR Grant

New NIH Grant awarded to InVivo Biosystems to address critical needs in precision medicine research

New NIH Grant awarded to InVivo Biosystems to address critical needs in precision medicine research using the model of C. elegans. The grant, titled “Functional Assessment of Variants in Organisms of Research (FAVOR) – Profiling Canonical Human Genes and their Variants through Disease Model Phenotyping” in the amount of $350,000 is awared by the Nation Human Genome Research Institute (NHGRI).

Read More »

Zebrafish Acute Toxicity Study Demonstrates Concordance with Rat Fetal Embryotoxicity

Summary: As the zebrafish is increasingly adopted to test drug toxicity, it is critical to systematically assess the parallels between zebrafish, humans and other model systems. In this article, we highlight a recent paper that compares toxicity results obtained in zebrafish and rats. The paper concludes that zebrafish are “valuable for predicting mammalian toxic exposure …

Zebrafish Acute Toxicity Study Demonstrates Concordance with Rat Fetal Embryotoxicity Read More »

The Challenge of Getting CRISPR-based Knock-ins to Work in Zebrafish

Just the other day, I was talking with a collaborator who told me that they didn’t really believe that knock-ins really worked in zebrafish. Although there have been literature reports for years, the number of labs that struggle and fail with this technique far outweigh the number that find success and publish. So I can …

The Challenge of Getting CRISPR-based Knock-ins to Work in Zebrafish Read More »

Scroll to Top