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Janis Weeks, Ph.D.

Flint water crisis. Man holding young girl.

Where the Lead Leads: Seeking Mechanisms of Action in C. elegans for Neurotoxic Effects of Lead

Neurotoxin exposure is implicated in the etiology of neurodegenerative diseases including Parkinson’s disease, Alzheimer’s disease and ALS (amyotrophic lateral sclerosis). Traditionally, vertebrate animals such as rodents and fish have been used for experimental work in neurotoxicology. However, researchers are increasingly turning to invertebrates such as the nematode, C. elegans, for a variety of compelling reasons

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The Evolution of Drug Resistance; an Issue of “When, not if”

Drug resistance in many pathogens — viruses, bacteria, protozoa, parasitic worms and more — presents a growing and potentially catastrophic challenge to human and animal health. Resistance is manifested by a decreased ability, or complete failure, of previously-effective drugs to successfully prevent or clear infections.  Well-known human examples include methicillin-resistant Staphylococcus aureas (MRSA); multi-drug resistant …

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