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Anna Malinkevich, MS

The Precisome™ Platform Bridges the ACDY5 Diagnostic Gap

NemaMetrix is the market leader for early preclinical in-vivo testing using small animal models to gain a better understanding of the efficacy, mode of action, toxicity and potential targets for novel compounds. In this case study we outline how we used the animal model C. elegans to perform a set of specific experiments designed by our experts to provide rapid and reliable data based on our customer’s priorities. Using the data that we provided, our customer was able to apply for multiple patents in a timely manner.

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Ask An Expert: The importance of experimental assay or analysis temperatures in C. elegans studies

Q: The Arena instrument maintains internal temperature – why is this important for C. elegans studies? A: The nematode C. elegans is commonly reared in the laboratory at temperatures between 15°C and 25°C, and worm growth and development drastically change even within this 10°C temperature range.  Worms reared at 20°C and 25°C will grow 1.3 …

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The Humanized Worm [Infographic]

Humanized model organisms are powerful biological models that allow scientists to study human disease genes in simpler contexts without losing the value of in vivo studies. In either C. elegans or Zebrafish, a native model organism gene can be replaced by a human gene with the same biological function. After this, mutations can be introduced into the …

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